Methadone is a commonly prescribed for treating opiate addictions and relieving chronic pain symptoms. A methadone-specific test is required to detect the drug’s presence in an individual’s system. People who have been using Methadone for long periods of time will have an extended detection window of 5 days after methadone use when using urine drug testing, and 90 days after use when using hair follicle drug testing. Some prescription drugs like ibuprofen may yield false positive drug test results for methadone. Gas Chromatography/Mass Spectrometry testing will confirm the presence of methadone metabolites in order to discern the drug from other cross-reactive substances.